EO-3021 is a monoclonal antibody conjugated commercialized by Elevation Oncology, with a leading Phase I program in Metastatic Pancreatic Cancer. According to Globaldata, it is involved in 3 clinical trials, of which 2 are ongoing, and 1 is planned. GlobalData uses proprietary data and analytics to provide a complete picture of EO-3021’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
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The revenue for EO-3021 is expected to reach an annual total of $10 mn by 2040 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
EO-3021 Overview
SYSA-1801 is under development for the treatment of metastatic gastric cancer, gastroesophageal junction adenocarcinoma, non-small cell lung cancer, esophageal cancer and pancreatic cancer. The drug candidate comprises of fully human anti-claudin-18.2 monoclonal antibody is conjugated with monomethyl auristatin E (MMAE). It is administered through intravenous drip route.
Elevation Oncology Overview
Elevation Oncology is a clinical-stage biopharmaceutical company focused on the development of precision medicines for patients. Elevation Oncology is headquartered in New York City, New York, the US.
The operating loss of the company was US$94.6 million in FY2022, compared to an operating loss of US$32.1 million in FY2021. The net loss of the company was US$95.1 million in FY2022, compared to a net loss of US$32 million in FY2021.
For a complete picture of EO-3021’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.
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To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.
