The Integrin Beta 7 pipeline drugs market research report outlays comprehensive information on the Integrin Beta 7 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Integrin Beta 7 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Gastrointestinal, Oncology, Immunology, and Infectious Disease which include the indications Ulcerative Colitis, Inflammatory Bowel Disease, Relapsed Multiple Myeloma, Refractory Multiple Myeloma, Graft Versus Host Disease (GVHD), and Human Immunodeficiency Virus (HIV) Infections (AIDS). It also reviews key players involved in Integrin Beta 7 targeted therapeutics development with respective active and dormant or discontinued products.
The Integrin Beta 7 pipeline targets constitutes close to 21 molecules. Out of which, approximately 20 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 2, 4, 5, 1, 5, and 3 respectively. Similarly, the universities portfolio in Phase I comprises 1 molecule.
Integrin Beta 7 overview
Integrin beta-7 is an integrin protein encoded by the ITGB7 gene. It interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. It binds to HIV-1 gp120 that allows the virus to enter GALT (major trigger of AIDS disease).
For a complete picture of Integrin Beta 7’s drug pipeline, buy the report here.
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