The Histone Deacetylase 2 pipeline drugs market research report outlays comprehensive information on the Histone Deacetylase 2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Histone Deacetylase 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Central Nervous System, Genetic Disorders, and Immunology which include the indications Melanoma, Non-Small Cell Lung Cancer, Parkinson’s Disease, Huntington Disease, Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and Systemic Lupus Erythematosus. It also reviews key players involved in Histone Deacetylase 2 targeted therapeutics development with respective active and dormant or discontinued products.
The Histone Deacetylase 2 pipeline targets constitutes close to 23 molecules. Out of which, approximately 18 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase II, Phase I, IND/ CTA Filed, and Preclinical stages are 3, 5, 1, 1, and 8 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 4, and 1 molecule.
Histone Deacetylase 2 overview
Histone deacetylase 2 is an enzyme encoded by the HDAC2 gene. It plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. It forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. It interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, and CAF1. It deacetylates TSHZ3 and regulates its transcriptional repressor activity.
For a complete picture of Histone Deacetylase 2’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
