BNT-113 is under clinical development by BioNTech and currently in Phase II for Penile Cancer. According to GlobalData, Phase II drugs for Penile Cancer does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the BNT-113 LoA Report. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
BNT-113 overview
BNT-113 is under development for the treatment of human papillomavirus (HPV) positive head and neck squamous cell carcinoma (HNSCC), cervical cancer, anogenital and penile cancer. The drug candidate is administered through intradermal and intravenous route. It is an mRNA therapeutic encoding human papillomavirus serotype 16 oncoproteins E6 and E7. It is developed based on FixVac technology (fixed combination of shared antigens).
BioNTech overview
BioNTech is a biotechnology company that develops immunotherapies for cancer and infectious diseases. The company’s primary activities involve harnessing the immune system to address diseases with unmet medical needs, utilizing a multi-technology innovation engine, GMP manufacturing, translational drug discovery, clinical development, commercial capabilities, computational medicine, data science, and artificial intelligence (AI) and machine learning (ML). BioNTech‘s product portfolio includes investigational mRNA vaccines, protein-based therapeutics, cell therapies, and small molecules. Its first marketed product is Comirnaty. The company’s products are designed to address the needs of cancer patients and combat infectious diseases. BioNTech collaborates with multiple global pharmaceutical companies, including Duality Biologics, Fosun Pharma, Genentech, Genevant, Genmab, OncoC4, Regeneron, and Pfizer. While the company operates globally, it aims to contribute to equitable access to medicine as part of its product strategy. BioNTech is headquartered in Mainz, Rhineland-Palatinate, Germany.
For a complete picture of BNT-113’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
