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Data Insights Innovation in pharma: microencapsulated peptide vaccines

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However, not all innovations are equal and nor do they follow a constant upward trend. Instead, their evolution takes the form of an S-shaped curve that reflects their typical lifecycle from early emergence to accelerating adoption, before finally stabilizing and reaching maturity.

Identifying where a particular innovation is on this journey, especially those that are in the emerging and accelerating stages, is essential for understanding their current level of adoption and the likely future trajectory and impact they will have.

80+ innovations will shape the pharmaceutical industry

According to GlobalData’s Technology Foresights, which plots the S-curve for the pharmaceutical industry using innovation intensity models built on over 730,000 patents, there are 80+ innovation areas that will shape the future of the industry.

Within the emerging innovation stage, engineered multi-specific antibodies, tyrosine kinase inhibitors, and mutant DNA polymerases are disruptive technologies that are in the early stages of application and should be tracked closely. Peptide pharmacophores, antibody-drug conjugates, and neuroprotective drugs are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are amyloid precursor targeted therapies and modified vector HIV-1 vaccines, which are now well established in the industry.

Innovation S-curve for the pharmaceutical industry

Microencapsulated peptide vaccines is a key innovation area in the pharmaceutical industry

Peptide vaccine microsphere formulations refer to a type of vaccine delivery system in which small particles made up of biodegradable polymers are used to encapsulate peptide antigens. These microspheres protect the peptide antigens from degradation and improve their stability and immunogenicity. When administered to a host, the microspheres slowly release the antigens over an extended period, allowing for a sustained immune response.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 1265+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of microencapsulated peptide vaccines.

Key players in microencapsulated peptide vaccines – a disruptive innovation in the pharmaceutical industry

‘Application diversity’ measures the number of applications identified for each patent. It broadly splits companies into either ‘niche’ or ‘diversified’ innovators.

‘Geographic reach’ refers to the number of countries each patent is registered in. It reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.

Patent volumes related to microencapsulated peptide vaccines

GSK is one of the leading patent filers in microencapsulated peptide vaccines. It is involved in the development of various peptide vaccines. GSK also acquired Affinivax, a leading company in vaccine development, primarily for cancer.

In terms of application diversity, Mitsubishi Chemical leads the pack, while Novavax and Centre national de la recherche scientifique (CNRS) stood in second and third positions, respectively.

By means of geographic reach, Vertex Pharmaceuticals held the top position, followed by F. Hoffmann-La Roche and X4 Pharmaceuticals.

To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.