Novan. has filed a patent for a composition and method of treating the skin. The composition includes various ingredients such as a diluent, solvent, penetration enhancing agent, skin brightening agent, skin renewing agent, thickening agent, anti-irritant, chelating agent, active pharmaceutical ingredient, pH adjustment agent, and preservative. The method involves applying the composition to a subject for skin treatment. GlobalData’s report on Novan gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Novan, Nanoparticle drug conjugates was a key innovation area identified from patents. Novan's grant share as of June 2023 was 1%. Grant share is based on the ratio of number of grants to total number of patents.
A recently filed patent (Publication Number: US20230144853A1) describes a method for treating a subject using a specific composition. The composition includes various ingredients such as water, alcohol, glycol ether, peptides, polyacrylate polymer, anti-irritant, chelating agent, and an active pharmaceutical ingredient (API) selected from salicylic acid, a nitric oxide (NO)-releasing compound, or a combination of both. The composition may also include L-arginine, L-citrulline, or derivatives thereof.
The method involves applying the composition topically to the subject. The composition is primarily water-based, with water accounting for about 60% to 95% of the composition's weight. The solvent used in the composition contains alcohol, specifically tert-butyl alcohol, which makes up about 1% to 20% of the composition's weight. A glycol ether called ethoxydiglycol is included as a penetration enhancing agent, present in about 1% to 10% of the composition's weight.
The composition also includes a skin brightening agent, which consists of a first peptide, and a skin renewal agent, which consists of a second peptide. These agents are present in amounts ranging from 0.1% to 10% of the composition's weight. A polyacrylate polymer is used as a thickening agent, making up about 0.1% to 5% of the composition's weight.
To ensure the composition is well-tolerated, it includes an anti-irritant in an amount of about 0.1% to 10% of the composition's weight. A chelating agent is also included, present in about 0.01% to 2% of the composition's weight. The API, which can be either salicylic acid or a NO-releasing compound, is present in amounts ranging from 0.1% to 10% of the composition's weight.
Optionally, the composition may include a pH adjustment agent and a preservative. The pH adjustment agent is present in about 0.01% to 3% of the composition's weight, while the preservative is present in the same range.
Overall, this patent describes a method for treating a subject using a specific composition that includes various ingredients in specific amounts. The composition aims to provide skin brightening and renewal effects while minimizing irritation. The inclusion of specific ingredients and their concentrations in the composition is intended to optimize its effectiveness and safety.
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