Enpatoran is under clinical development by Merck and currently in Phase II for Subacute Cutaneous Lupus Erythematosus (SCLE). According to GlobalData, Phase II drugs for Subacute Cutaneous Lupus Erythematosus (SCLE) does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Enpatoran LoA Report. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Enpatoran overview
Enpatoran (M-5049) is under development for the treatment of Coronavirus disease 2019 pneumonia, cutaneous lupus erythematosus, systemic lupus erythematosus, subacute cutaneous lupus erythematosus [SCLE], discoid lupus erythematosus [DLE]), neuromuscular conditions dermatomyositis and polymyositis. It is administered by oral route. The drug candidate is a new chemical entity. It acts by targeting toll like receptor 7/8.
Merck overview
Merck, a subsidiary of E. Merck KG, is a science and technology company. It discovers, develops, and manufactures prescription drugs to treat cancer, multiple sclerosis, and infertility; and develops liquid crystal mixtures, organic light-emitting diode (OLED) materials, cosmetic active ingredients, pigments for coatings, and high-tech materials. Merck also provides a wide range of products including lab water systems, gene editing tools, cell lines, antibodies, microbiology and biomonitoring products, test assays, analytical reagents, and flow cytometry kits and instruments and end-to-end systems. The company serves healthcare, performance materials, and life sciences markets. It has presence in Europe, North America, Asia-Pacific, Latin America and Middle East and Africa. Merck is headquartered in Darmstadt, Hesse, Germany.
For a complete picture of Enpatoran’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
