JNJ-8543 is under clinical development by Johnson & Johnson and currently in Phase I for Waldenstrom Macroglobulinemia (Lymphoplasmacytic Lymphoma). According to GlobalData, Phase I drugs for Waldenstrom Macroglobulinemia (Lymphoplasmacytic Lymphoma) have a 72% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how JNJ-8543’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
JNJ-8543 overview
JNJ-80948543 is under development for the treatment of chronic lymphocytic leukemia (CLL), waldenstrom macroglobulinemia (lymphoplasmacytic lymphoma), mantle cell lymphoma, follicular lymphoma, diffuse large b-cell lymphoma, marginal zone b-cell lymphoma including nodal marginal zone b-cell lymphoma, extranodal marginal zone b-cell lymphoma (mucosa-associated lymphoid tissue or malt-lymphoma), splenic marginal zone b-cell lymphoma, hematological malignancies. The drug candidate is administered through subcutaneous route. It is a T-cell redirecting tri-specific antibody that recognizes the cluster of differentiation 3 (CD3) on T lymphocytes and and CD79b, and CD20 surface antigens on mature healthy and malignant B-lymphocytes.
Johnson & Johnson overview
Johnson & Johnson (J&J) researches, develops, manufactures, and sells pharmaceutical products and medical devices. The company conducts business through its operating companies. It provides pharmaceuticals for immune disorders, cancer, neurological disorders, infectious, cardiovascular, and metabolic diseases; and medical devices for use in cardiovascular, orthopaedic, neurovascular care, general surgery and vision care fields. J&J distributes pharmaceutical and medical products to retailers, wholesalers, healthcare professionals and hospitals. The company offers its products in the US; Europe; Asia-Pacific and Africa; and Western Hemisphere (excluding the US) and Latin America. J&J is headquartered in New Brunswick, New Jersey, the US.
For a complete picture of JNJ-8543’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
