Shape Therapeutics has signed a multi-target strategic partnership and licence agreement with Roche to develop gene therapy for specific targets in Alzheimer’s disease, Parkinson’s disease, and rare disease areas.
The deal means Shape is eligible to more than $3bn from Roche in initial and potential payments on meeting development, regulatory and sales milestones.
How well do you really know your competitors?
Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.
Thank you!
Your download email will arrive shortly
Not ready to buy yet? Download a free sample
We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form
By GlobalDataShape is also entitled to tiered royalty payments on future sales of products developed through the partnership.
The alliance will use Shape’s RNA editing platform, RNAfix, and the AAVid technology platform for tissue-specific adeno-associated viruses (AAVs) to create gene therapy for neuroscience and rare disease indications.
Shape Therapeutics co-founder and CEO Francois Vigneault said: “Our mission at Shape is to unlock the next breakthrough in RNA technologies in the gene therapy space across a wide range of therapeutic areas.
“The relationship with Roche quickly centred on a common desire to tackle some of the world’s most challenging diseases by accelerating the development of breakthrough technologies towards the clinic.”
Shape will oversee the preclinical research to detect and offer development candidates discovered using its artificial intelligence (AI)-driven RNAfix and AAVid platforms.
Roche will lead the development and global marketing of any products potentially developed through the alliance.
Roche Pharma Partnering head James Sabry said: “This new collaboration is also perfectly aligned with our broader efforts across the Roche Group to unlock the full potential of gene therapy.
“We look forward to working with Shape to create novel treatment options for neuroscience and rare disease indications.”
Last month, Roche reported an 8% increase in group sales to $33.46bn (CHF30.71bn) at constant exchange rates (CER) in the first half (H1) of 2021, against $31.81bn (CHF29.28bn) in H1 of last year.
Cell & Gene Therapy Coverage on Pharmaceutical Technology supported by Cytiva.
Editorial content is independently produced and follows the highest standards of journalistic integrity. Topic sponsors are not involved in the creation of editorial content.
